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In cases of systemic hematogenous dissemination of malignant tumors, the embolic influx into the various tissues must be proportional to their respective arterial blood supplies, yet such richly vascular organs as the intestine, spleen and thyroid gland are relatively infrequent sites for secondary growths resulting from hematogenous spread. Taking the total weights of the liver and thyroid to be 1500 and 25 grams respectively, it appears that the thyroid actually receives about one-half the volume of arterial blood received by the entire liver. Yet, while the liver is very frequently the seat of metastases derived from the systemic blood stream,
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Metastatic Tumors in the Thyroid Gland.. Ann Intern Med. 1931;5:389–390. doi: 10.7326/0003-4819-5-3-389_2
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Published: Ann Intern Med. 1931;5(3):389-390.
Endocrine and Metabolism, Hematology/Oncology, Thyroid Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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