MILTON S. SACKS, B.S., M.D.
The occurrence of adrenal hemorrhages of varying degree is a matter of common clinical and pathological knowledge in such conditions as diphtheria, scarlet fever, measles, and pneumonia. In new-born and still-born infants, adrenal hemorrhage, likewise, is known to occur and is chiefly of mechanical or traumatic origin. Snelling and Erb1 found 43 cases of adrenal hemorrhage in 3,637 consecutive autopsies, an incidence of 1.19 per cent. Of these, 15 occurred in the new-born. In older children adrenal hemorrhage is usually of toxic or infectious etiology.
The association of fulminating purpura with bilateral adrenal hemorrhage has long been recognized. The earliest
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SACKS MS. FULMINATING SEPTICEMIA ASSOCIATED WITH PURPURA AND BILATERAL ADRENAL HEMORRHAGE (WATERHOUSE-FRIDERICHSEN SYNDROME); REPORT OF TWO CASES WITH REVIEW OF THE LITERATURE(FULMINATING SEPTICEMIA ASSOCIATED WITH PURPURA AND BILATERAL ADRENAL HEMORRHAGE (WATERHOUSE-FRIDERICHSEN SYNDROME); REPORT OF TWO CASES WITH REVIEW OF THE LITERATURE*). Ann Intern Med. 1937;10:1105–1114. doi: 10.7326/0003-4819-10-8-1105
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Published: Ann Intern Med. 1937;10(8):1105-1114.
Adrenal Disorders, CNS Infections, Coagulopathies, Endocrine and Metabolism, Hematology/Oncology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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