ELLIS W. WILLHELMY, M.D.
In 1923, Mann and Williamson1 reported that they were able to produce in dogs subacute and chronic peptic ulcers, quite like those found in man, by diverting to another part of the intestine those secretions of the duodenum which normally neutralize the gastric juice as it leaves the stomach.
Aron and Weiss2 of Strasbourg repeated and confirmed these studies. They came to the conclusion that these ulcers formed as a result of an amino acid deficiency. On this theory, they gave intramuscular injections of certain amino acids to dogs that had been subjected to the Mann-Williamson technic, and found that
Learn more about subscription options.
Register Now for a free account.
WILLHELMY EW. FURTHER OBSERVATIONS OF THE HISTIDINE TREATMENT OF PEPTIC ULCER(FURTHER OBSERVATIONS OF THE HISTIDINE TREATMENT OF PEPTIC ULCER*). Ann Intern Med. 1937;10:1365–1370. doi: 10.7326/0003-4819-10-9-1365
Download citation file:
Published: Ann Intern Med. 1937;10(9):1365-1370.
Gastroenterology/Hepatology, Peptic Disease, Peptic Ulcer.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only