A. T. KWEDAR, M.D.
The presence of purpuric or petechial spots on the skin, associated with a massive hemorrhagic destruction of both adrenals and the presence of a fulminating septicemia, is recognized as the Waterhouse-Friderichsen syndrome.1
Seventy per cent of all cases reported are in children under the age of two years. This may be owing to the susceptibility and lack of immunity of children to the meningococcus. In Aegerter's2 review of the literature he found only six cases of Waterhouse-Friderichsen syndrome occurring in adults, only three of whom were over 50 years of age. Foucar,3 in 1936, reported one case in a 20
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KWEDAR AT. THE WATERHOUSE-FRIDERICHSEN SYNDROME: REPORT OF A CASE IN AN ADULT(THE WATERHOUSE-FRIDERICHSEN SYNDROME: REPORT OF A CASE IN AN ADULT*). Ann Intern Med. 1942;16:787–791. doi: 10.7326/0003-4819-16-4-787
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Published: Ann Intern Med. 1942;16(4):787-791.
Adrenal Disorders, CNS Infections, Endocrine and Metabolism, Infectious Disease, Neurology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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