MOSES SALZER, M.D.; J. LOUIS RANSOHOFF, M.D.; BLATT HERMANN, M.D.
About one year ago Wiseman and Doan1 published a report of five cases of "a hitherto unrecognized cause of neutropenia resulting from a pathologically altered, physiologic function of the normal spleen." They labelled this disease "primary splenic neutropenia." They postulated the theory that the spleen has a selective destructive action on the various cellular components of the blood. For instance, in thrombocytopenia, this selective destructive function destroyed the thrombocytes at an abnormally high rate; in hemolytic jaundice the erythrocytes were selected for destruction, whereas in "primary splenic neutropenia" the neutrophiles were the victim of this selective action. In no instance
Learn more about subscription options.
Register Now for a free account.
SALZER M, RANSOHOFF JL, HERMANN B. PRIMARY SPLENIC NEUTROPENIA, WITH REPORT OF A CASE(PRIMARY SPLENIC NEUTROPENIA, WITH REPORT OF A CASE*). Ann Intern Med. 1945;22:271–273. doi: 10.7326/0003-4819-22-2-271
Download citation file:
Published: Ann Intern Med. 1945;22(2):271-273.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only