NOYES L. AVERY JR.; ORLANDO B. MAYER; ROBERT C. NELSON
Recently an impressively high percentage of apparent cures in cases of subacute bacterial endocarditis has been reported by treatment with penicillin. In most of these cases the infecting organism has been a Streptococcus viridans. Some strains of this organism, unfortunately have been resistant to penicillin. We wish to report such a case which, although apparently incurable with rather large doses of penicillin, did respond favorably when massive doses of penicillin were employed in the presence of a renal blockage with diodrast and sodium p-aminohippurate. It should be noted that in this case, during the 17 month period in which various
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AVERY NL, MAYER OB, NELSON RC. MASSIVE DOSES OF PENICILLIN IN THE TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITIS(MASSIVE DOSES OF PENICILLIN IN THE TREATMENT OF SUBACUTE BACTERIAL ENDOCARDITIS*). Ann Intern Med. 1946;24:900–904. doi: 10.7326/0003-4819-24-5-900
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Published: Ann Intern Med. 1946;24(5):900-904.
Cardiology, Endocarditis, Infectious Disease, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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