ALVIN P. SHAPIRO, M.D.; EUGENE B. FERRIS, M.D., F.A.C.P.
Recent studies by Freis and his co-workers have demonstrated that veratrum viride produces a fall in blood pressure not associated with a change in cardiac output or a significant diminution in blood flow to vital organs. The effects are generally vasodilator and may be mediated through the central nervous system.
Freis2 and Hite3 have shown that the blood pressure can be significantly lowered in most hypertensive patients when veratrum viride is given orally in sufficient amount; however, effective dosage varies widely and must be determined by individual trial in each patient. Since the preparations employed were extracts of mixtures
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SHAPIRO AP, FERRIS EB. THE EFFECTS OF INTRAVENOUSLY ADMINISTERED VERATRUM VIRIDE IN HYPERTENSIVE AND NORMOTENSIVE SUBJECTS(THE EFFECTS OF INTRAVENOUSLY ADMINISTERED VERATRUM VIRIDE IN HYPERTENSIVE AND NORMOTENSIVE SUBJECTS*). Ann Intern Med. 1952;36:792–806. doi: 10.7326/0003-4819-36-3-792
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Published: Ann Intern Med. 1952;36(3):792-806.
Cardiology, Coronary Risk Factors, Hospital Medicine, Hypertension, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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