BERNARD I. LEWIS, M.D., F.R.C.P.(C)., F.A.C.P.
The hyperventilation syndrome is generally considered an acute, transitory episode characterized by gross hyperpnea and culminating in frank tetany. Because of its presumed low incidence and clinical insignificance, it has received scanty attention in the current literature and is virtually ignored by the standard medical texts. Recent observations at the University Hospitals of the State University of Iowa College of Medicine suggest that, contrary to prevalent opinion, hyperventilation syndromes occur frequently; pursue a chronic, fluctuating course more often than one featuring brief, explosive attacks with asymptomatic intervals; present variegated, atypical clinical pictures, commonly attended by significant incapacitation; and may arise
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LEWIS BI. THE HYPERVENTILATION SYNDROME(THE HYPERVENTILATION SYNDROME*). Ann Intern Med. 1953;38:918–927. doi: 10.7326/0003-4819-38-5-918
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Published: Ann Intern Med. 1953;38(5):918-927.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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