ALFRED S. EVANS; HELMUTH SPRINZ; ROBERT S. NELSON
In the preceding paper1 it has been shown that administration of adrenocorticotropic hormone (ACTH) to 20 patients with acute viral hepatitis was associated with symptomatic improvement and a rapid initial drop in serum bilirubin as compared with control patients. This effect on bilirubinemia became progressively less marked as the drug was continued. The eosinophil response was, in general, poor. The average total duration of illness was not materially affected. It seemed possible that adrenal cortical exhaustion was responsible in part for these phenomena, and that direct substitution therapy with cortisone might be more effective and at the same time lessen
Learn more about subscription options.
Register Now for a free account.
EVANS AS, SPRINZ H, NELSON RS. ADRENAL HORMONE THERAPY IN VIRAL HEPATITIS. II. THE EFFECT OF CORTISONE IN THE ACUTE DISEASE(ADRENAL HORMONE THERAPY IN VIRAL HEPATITIS. II. THE EFFECT OF CORTISONE IN THE ACUTE DISEASE*). Ann Intern Med. 1953;38:1134–1147. doi: 10.7326/0003-4819-38-6-1134
Download citation file:
Published: Ann Intern Med. 1953;38(6):1134-1147.
Gastroenterology/Hepatology, Infectious Disease, Liver Disease, Viral Hepatitis.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only