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This is a brief monograph, well worth reading, on trends in therapy in the treatment of peripheral vascular disease.
The influence of George E. Brown in the field of peripheral vascular disease is briefly summarized, as well as attitudes in therapy previous to 1928. The transition toward conservative treatment based on physiologic principles is stressed.
The histamine test and its concept is described.
Physiological methods of treatment comprise: (1) Reducing as much as possible the need for blood in the area supplied by the obstructed vessels; (2) increasing the supply of blood as much as possible by dilating the vessels
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Physiologic Therapy for Obstructive Vascular Disease.. Ann Intern Med. 1953;38:1348. doi: 10.7326/0003-4819-38-6-1348_1
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Published: Ann Intern Med. 1953;38(6):1348.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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