BUFORD HALL, M.D.
Aureomycin has now been in clinical use for more than five years. The voluminous and still growing literature concerned with this antibiotic relates chiefly to its clinical trial in various diseases, there being relatively few studies of its distribution in various body fluids. This situation may be partly explained by technical difficulties resulting from instability of Aureomycin solutions at room temperature, particularly at a neutral pH.1 In this paper we propose to summarize the knowledge concerning the absorption, diffusion and excretion of Aureomycin after oral administration, based on data in the literature and on more than 400 previously unreported determinations
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HALL B. THE ABSORPTION AND DISTRIBUTION OF AUREOMYCIN IN MAN: A REVIEW OF THE LITERATURE AND STUDY OF THE CONCENTRATION OF AUREOMYCIN IN THE SERUM, URINE AND CEREBROSPINAL FLUID AFTER ORAL ADMINISTRATION(THE ABSORPTION AND DISTRIBUTION OF AUREOMYCIN IN MAN: A REVIEW OF THE LITERATURE AND STUDY OF THE CONCENTRATION OF AUREOMYCIN IN THE SERUM, URINE AND CEREBROSPINAL FLUID AFTER ORAL ADMINISTRATION*). Ann Intern Med. 1954;40:743–754. doi: 10.7326/0003-4819-40-4-743
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Published: Ann Intern Med. 1954;40(4):743-754.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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