U. S. VON EULER, F.A.C.P. (Hon.), M.D.
The therapeutic use of noradrenalin was suggested by Biberfeld3 in Austria half a century ago because of its strong vasoconstrictor action and low toxicity, but his plea for the new drug evoked no response, and interest in noradrenalin as a drug was almost negligible before the late forties. Since that time the number of investigations dealing with its therapeutic applications has grown rapidly.
Probably the most valuable and informative basis for the rational use of noradrenalin is its function as sympathetic nerve transmitter and suprarenal medullary hormone.5, 6, 16 Incidentally, the old claim that the so-called natural adrenalin from suprarenal
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VON EULER US. PHYSIOLOGIC BASIS FOR THE CLINICAL USE OF NORADRENALIN(PHYSIOLOGIC BASIS FOR THE CLINICAL USE OF NORADRENALIN*). Ann Intern Med. 1954;41:699–708. doi: 10.7326/0003-4819-41-4-699
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Published: Ann Intern Med. 1954;41(4):699-708.
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