W. RAAB, M.D., F.A.C.P.
Three cardinal features of cardiac pathology—myocardial hypertrophy, myocardial structural degeneration and myocardial functional weakness—are by tradition ascribed to primarily mechanical factors, namely, increased hemodynamic resistance or decreased coronary blood flow or both. The inadequacy of such oversimplification is becoming increasingly obvious in the light of our growing comprehension of underlying myocardial metabolic anomalies, especially those induced or enhanced by the action of neurohormones (adreno-sympathogenic catecholamines) and hormones (adrenal mineralo-corticoids and thyroid hormone).
1. The phenomenon of cardiac hypertrophy depends to a much lesser extent on the mechanical "burden" of increased peripheral resistance than is generally believed. This is exemplified by
Learn more about subscription options.
Register Now for a free account.
RAAB W. HORMONAL FACTORS IN HEART DISEASE: THEIR ROLE IN MYOCARDIAL HYPERTROPHY, HYPOXIA AND ELECTROLYTE IMBALANCE(HORMONAL FACTORS IN HEART DISEASE: THEIR ROLE IN MYOCARDIAL HYPERTROPHY, HYPOXIA AND ELECTROLYTE IMBALANCE*). Ann Intern Med. 1954;41:757–763. doi: 10.7326/0003-4819-41-4-757
Download citation file:
Published: Ann Intern Med. 1954;41(4):757-763.
Cardiology, Endocrine and Metabolism, Fluid and Electrolyte Disorders, Nephrology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only