JOSEPH K. PERLOFF, M.D.; ELBERT T. PHELPS, M.D., F.A.C.P.
In 1868 Rothmund1 published his observations on "Cataracts in Association with a Peculiar Degeneration of the Skin," a heredofamilial disorder found in the consanguineous populations of three small Bavarian villages. Thirty-six years later another German ophthalmologist, Werner,2 independently described an odd syndrome entitled "Cataract in Connection with Scleroderma," involving two sisters in a family of six siblings.
Further observations were not published until material from German and French sources appeared in the 1920's. However, no distinction between these two syndromes was made until the first report in the American medical literature in 1934, when Oppenheimer and Kugel3 distinguished the conditions
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PERLOFF JK, PHELPS ET. A REVIEW OF WERNER'S SYNDROME, WITH A REPORT OF THE SECOND AUTOPSIED CASE(A REVIEW OF WERNER'S SYNDROME, WITH A REPORT OF THE SECOND AUTOPSIED CASE*). Ann Intern Med. 1958;48:1205–1220. doi: 10.7326/0003-4819-48-6-1205
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Published: Ann Intern Med. 1958;48(6):1205-1220.
Hematology/Oncology, Hospital Medicine, Lupus Erythematosus, Rheumatology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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