MONROE THOMAS DIAMOND, M.D., F.A.C.P.
Although hypertrophic osteoarthropathy has been noted in association with a wide variety of primary disorders,1 its occurrence with diseases of the thyroid has been little mentioned in the literature. In 1919 Ebstein2 briefly reported a case of clubbing of the fingers developing in a 24 year old male following thyroidectomy for exophthalmic goiter. Thomas3 in 1933 described in detail a patient who, eight months after having had a subtotal thyroidectomy for exophthalmic goiter, developed progressive hypertrophic osteoarthropathy and a concurrent brawny and pigmented edema of the legs consistent with myxedema. Thomas felt that the rapid change in thyroid function following
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DIAMOND MT. THE SYNDROME OF EXOPHTHALMOS, HYPERTROPHIC OSTEOARTHROPATHY AND LOCALIZED MYXEDEMA: A REVIEW OF THE LITERATURE AND REPORT OF A CASE*. Ann Intern Med. 1959;50:206–213. doi: 10.7326/0003-4819-50-1-206
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Published: Ann Intern Med. 1959;50(1):206-213.
Endocrine and Metabolism, Thyroid Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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