JONAS E. SALK, M.D.
When one reflects upon the growing evidence that a killed-virus vaccine is likely to bring about the control of paralytic polio, there comes to mind the definition of science quoted by Gustafson1 as that body of knowledge obtained by technics that enable us to place limiting values on our preconceptions.
I recall the general statement I first heard more than 20 years ago—that immunity to a virus disease had not been, or could not be, induced by a killed-viral antigen. Less than a decade ago (and, in some quarters, today), the more acceptable view was that the control of polio,
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SALK JE. PRECONCEPTIONS ABOUT VACCINATION AGAINST PARALYTIC POLIOMYELITIS(PRECONCEPTIONS ABOUT VACCINATION AGAINST PARALYTIC POLIOMYELITIS*). Ann Intern Med. 1959;50:843–861. doi: 10.7326/0003-4819-50-4-843
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Published: Ann Intern Med. 1959;50(4):843-861.
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