PHILIP LISAN, M.D.; ATTILIO REALE, M.D.; WILLIAM LIKOFF, M.D., F.A.C.P.
A phasic recurrent fever occurring at variable times, mainly after mitral valve surgery, associated with incisional and/or pleuritic pain, has been called the postmitral commissurotomy syndrome. The etiology of this peculiar syndrome is unknown, but speculation has ranged from rheumatic reactivation and idiopathic pleuropericarditis to a hypersensitivity reaction from nonspecific antigens such as blood in the pleural or pericardial sacs postoperatively.1, 2
Considerable evidence favors the view that the postmitral commissurotomy syndrome represents reactivation of the rheumatic state.3, 4 The temperature elevation is low grade and cyclic, and is associated with myalgias or true migrating polyarthralgias. It is accompanied by
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LISAN P, REALE A, LIKOFF W. THE POSTMITRAL COMMISSUROTOMY SYNDROME: A FOUR-YEAR CLINICAL, PATHOLOGIC AND SEROLOGIC STUDY, AND ITS RELATION TO RESTENOSIS(THE POSTMITRAL COMMISSUROTOMY SYNDROME: A FOUR-YEAR CLINICAL, PATHOLOGIC AND SEROLOGIC STUDY, AND ITS RELATION TO RESTENOSIS*). Ann Intern Med. 1959;50:1352–1358. doi: 10.7326/0003-4819-50-6-1352
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Published: Ann Intern Med. 1959;50(6):1352-1358.
Cardiology, Valvular Heart Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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