H. J. ROBERTS, M.D.
This paper reports a patient with a bronchogenic carcinoma who developed profound hyponatremia and hypochloremia in association with considerable loss of both sodium and chloride in the urine. Clinically he was found to have normal renal and adrenal function and at autopsy the kidneys and the adrenals showed no significant pathologic change.
Two earlier instances of this particular syndrome were included in the report by Schwartz et al. in 1957.1 It was the opinion of these investigators that this unusual electrolyte derangement could best be explained by a sustained and inappropriate secretion of antidiuretic hormone, and that this disorder was
Learn more about subscription options.
Register Now for a free account.
ROBERTS HJ. THE SYNDROME OF HYPONATREMIA AND RENAL SODIUM LOSS PROBABLY RESULTING FROM INAPPROPRIATE SECRETION OF ANTIDIURETIC HORMONE(THE SYNDROME OF HYPONATREMIA AND RENAL SODIUM LOSS PROBABLY RESULTING FROM INAPPROPRIATE SECRETION OF ANTIDIURETIC HORMONE*). Ann Intern Med. 1959;51:1420–1426. doi: 10.7326/0003-4819-51-6-1420
Download citation file:
Published: Ann Intern Med. 1959;51(6):1420-1426.
Endocrine and Metabolism, Fluid and Electrolyte Disorders, Nephrology, Neurology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only