ROBERT R. BURCH, M.D.; MAURICE A. PEARL, M.D.; WILLIAM H. STERNBERG, M.D.
The nephrotic syndrome is a disorder of diverse causes which occurs as a primary or secondary form of renal disease and exhibits variable pathologic features (1-8). Its etiologic and pathologic variations pose many problems of diagnosis and therapy. However, a pathologic diagnosis can now be made by a percutaneous renal biopsy. Such biopsies have revealed the broad spectrum of histopathologic changes found in the group of diseases responsible for the nephrotic syndrome (5-14). The multiple glomerular changes revealed by renal biopsies may help to explain the marked variation in the clinical course, as well as unpredictable and variable responses to
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BURCH RR, PEARL MA, STERNBERG WH. A Clinicopathological Study of the Nephrotic Syndrome. Ann Intern Med. 1962;56:54–67. doi: 10.7326/0003-4819-56-1-54
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Published: Ann Intern Med. 1962;56(1):54-67.
Nephrology, Nephrotic Syndrome.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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