LAWRENCE E. MELTZER, M.D.; FLORENTINO P. PALMON, M.D.; YOUNG K. PAIK, M.D.; R. PHILIP CUSTER, M.D.
MELTZER LE, PALMON FP, PAIK YK, CUSTER RP. Acute Pancreatitis Secondary to Hypercalcemia of Multiple Myeloma. Ann Intern Med. 1962;57:1008-1012. doi: 10.7326/0003-4819-57-6-1008
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Published: Ann Intern Med. 1962;57(6):1008-1012.
The observation by Cope, Culver, Mixter, and Nardi (1) in 1957 that pancreatitis may complicate hyperparathyroidism has been amply confirmed. More than 60 cases in which these 2 states existed concomitantly have been reported (2, 3). This etiologic relationship appears to be well enough established to warrant the advice that patients with pancreatitis be studied appropriately in order to exclude hyperparathyroidism, even when the more common manifestations of this disease are absent (4).
The mechanism by which pancreatitis occurs in the presence of hyperparathyroidism has not been fully explained and remains controversial. Several hypotheses have been presented. It has been
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Endocrine and Metabolism, Fluid and Electrolyte Disorders, Gastroenterology/Hepatology, Hematology/Oncology, Multiple Myeloma.
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