ROBERT M. DONATI, M.D.; JOHN M. MCCARTHY, M.D.; ROBERT D. LANGE, M.D., F.A.C.P.; NEIL I. GALLAGHER, M.D.
Erythrocythemia has been observed in patients with several types of malignant and non-malignant tumors (1-65). Hematologic remissions following extirpation of the tumor (1-8, 10-14, 29-39, 60, 61) have suggested a causal relationship apparently due to elaboration of an erythropoietic factor by the neoplastic tissue. This report details observations made in 4 patients with erythrocythemia in association with undifferentiated carcinoma of the lung, hepatic cell carcinoma, or renal cell carcinoma. Plasma obtained from 3 of these patients exhibited erythropoietic stimulating activity.
Clinical summaries are recorded below. Only pertinent historical data, physical findings, and diagnostic examinations are included. Results
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DONATI RM, MCCARTHY JM, LANGE RD, GALLAGHER NI. Erythrocythemia and Neoplastic Tumors. Ann Intern Med. 1963;58:47–55. doi: 10.7326/0003-4819-58-1-47
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Published: Ann Intern Med. 1963;58(1):47-55.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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