LARKIN M. WILSON, M.D.
The occurrence, prognosis, and clinical course of many severe bacterial infections have been greatly improved with the development of effective antimicrobial agents. There is well-documented evidence that with these drugs has come a change in bacterial flora within the population, as well as an alteration in the etiologic organisms of several specific infectious entities (1-3).
In view of this shift in etiology, it would seem reasonable to ask if there has been a corresponding change in the pathology of the specific infectious diseases since the introduction of antibiotics. Kneeland and Price have shown that the organisms formerly considered to be
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WILSON LM. Pathology of Fatal Bacterial Endocarditis before and since the Introduction of Antibiotics. Ann Intern Med. 1963;58:84–92. doi: 10.7326/0003-4819-58-1-84
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Published: Ann Intern Med. 1963;58(1):84-92.
Cardiology, Endocarditis, Infectious Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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