NEAL A. VANSELOW, M.D.; VERNON N. DODSON, M.D.; DAVID C. ANGELL, M.D.; IVAN F. DUFF, M.D., F.A.C.P.
The association of rheumatoid arthritis, keratoconjunctivitis sicca, and xerostomia, with or without swelling of the salivary glands, has been termed Sjögren's syndrome. Since the initial description by Henrik Sjögren in 1933 (1), clinical studies have demonstrated the not uncommon occurrence of purpura, Raynaud's phenomenon, achylia gastrica, alopecia, splenomegaly, and leukopenia, as well as dryness of the skin, nasal mucosa, and larynx in patients with this disorder. A close relationship with connective tissue diseases other than rheumatoid arthritis has been suggested by the observation that systemic lupus erythematosus (2), scleroderma (3), periarteritis nodosa (4), or polymyositis (5) may in some instances
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VANSELOW NA, DODSON VN, ANGELL DC, DUFF IF. A Clinical Study of Sjögren's Syndrome. Ann Intern Med. 1963;58:124–135. doi: 10.7326/0003-4819-58-1-124
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Published: Ann Intern Med. 1963;58(1):124-135.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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