JOEL M. GROSS, M.D.
Lignac in 1924 described a special form of infantile rickets which seemed to be closely associated with an abnormality in cystine metabolism. Comparable observations were made by Fanconi in 1931, by de Toni in 1933, and by Debré in 1934. In 1936, Fanconi (1) concluded that in this special form of rickets a deficient reabsorption of different substances occurs in the proximal convoluted tubules of the kidney.
The Lignac-Fanconi syndrome as seen in children appears to be a genetically determined disorder of renal tubular function inherited as a simple mendelian recessive characteristic, and the disorder is commonly limited to the
Learn more about subscription options.
Register Now for a free account.
GROSS JM. Fanconi Syndrome (Adult Type) Developing Secondary to the Ingestion of Outdated Tetracycline. Ann Intern Med. 1963;58:523–528. doi: 10.7326/0003-4819-58-3-523
Download citation file:
Published: Ann Intern Med. 1963;58(3):523-528.
Hospital Medicine, Nephrology, Urological Disorders.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only