JAMES H. JANDL, M.D.
With the development of the chemical industry in Germany about a century ago, a prevalent, often severe form of poisoning appeared among workers exposed to certain coal tar derivatives. This consisted of an acute hemolytic process having 2 characteristic features: a brown-to-green discoloration of the blood, creating a form of cyanosis when viewed in the patient; and the presence of inclusion bodies in the red cells that were evident on supravital staining and were called "Heinz bodies" (1). Most such reactions were provoked by aromatic compounds possessing amino, nitro, or hydroxy groups, of which the most notorious were aniline, nitrobenzene,
Learn more about subscription options.
Register Now for a free account.
JANDL JH. The Heinz Body Hemolytic Anemias. Ann Intern Med. 1963;58:702-709. doi: 10.7326/0003-4819-58-4-702
Download citation file:
Published: Ann Intern Med. 1963;58(4):702-709.
Hematology/Oncology, Red Cell Disorders.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only