B. Lown, M.D.
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Since the introduction of quinidine by Frey, 45 years ago, drugs have been the mainstay in the treatment of ectopic arrhythmias. A new method of treatment has now been introduced which no longer depends on drugs. This method, cardioversion, is based on 2 key principles.
1. The heart can be depolarized across the intact chest by a brief direct-current (d-c) electrical discharge and thereby result in abolition of an ectopic arrhythmia.
2. When the d-c discharge is synchronized to fall outside the vulnerable period of the cardiac cycle, the discharge is entirely without hazard to the patient.
Cardioversion has now
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Lown B. The Termination of Cardiac Arrhythmias with Electrical Discharge.. Ann Intern Med. 1963;58:713. doi: 10.7326/0003-4819-58-4-713_2
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Published: Ann Intern Med. 1963;58(4):713.
Cardiology, Rhythm Disorders and Devices.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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