M. McIlroy, M.D.
McIlroy M. Reduced Hemoglobin Dilution Curves in the Assessment of Cardiovascular Function.. Ann Intern Med. 1963;58:716. doi: 10.7326/0003-4819-58-4-716_1
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Published: Ann Intern Med. 1963;58(4):716.
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When the alveolar oxygen tension is suddenly lowered for several seconds and then raised above its initial level, the blood leaving the lungs temporarily contains an increased concentration of reduced hemoglobin (Hb). This procedure is equivalent to the pulmonary capillary blood. The principles governing the detection of changes in concentration of this indicator at a distant sampling site with an ear oximeter are similar to those used in conventional indicators. After a deep exhalation the subject takes a single deep breath of nitrogen, breathes out, and takes a single deep breath of oxygen. The effect of the deep breath of
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