R. C. Reynolds, M.D. (Associate); F. I. Catlin, M.D.; L. E. Cluff, M.D., F.A.C.P.
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Fifty patients with acute maxillary sinusitis were studied to determine the bacteriology of this infection and its response to antibiotic therapy. Diagnosis was established in all cases by directly observing purulent discharge from the ostium of the infected sinus and antral clouding upon transillumination. Sinus discharge or antral washings provided the material for culture. The antibiotic sensitivity of the recovered microorganisms was recorded, and all coagulase-positive staphylococci were phage typed.
Initially, patients were placed on a 5-day course of one antibiotic (erythromycin, tetracycline, or penicillin) or a placebo. Double blind controls were used in administration of antibiotics and placebo. Subsequent
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Reynolds RC, Catlin FI, Cluff LE. Bacteriology and Therapy of Acute Maxillary Sinusitis.. Ann Intern Med. 1963;58:734-735. doi: 10.7326/0003-4819-58-4-734_4
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Published: Ann Intern Med. 1963;58(4):734-735.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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