J. G. Barrow, M.D., F.A.C.P.; R. A. Naiman, M.D.
Barrow JG, Naiman RA. Penicillin Resistant Bacteria in the Mouths and Throats of Children on Continuous Prophylaxis against Rheumatic Fever.. Ann Intern Med. 1963;58:735. doi: 10.7326/0003-4819-58-4-735_2
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Published: Ann Intern Med. 1963;58(4):735.
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Since bacterial endocarditis caused by alpha streptococci has been shown to be a particularly serious event in the management of patients with rheumatic heart disease, and because infection with penicillin-resistant strains of alpha streptococci might well pose a therapeutic problem in treatment, an investigation comparing the mouth flora of 3 groups of individuals living free in the community was carried out. A total of 74 persons was studied, including 8 normal individuals and 66 patients of whom 45 were receiving sulfadiazine prophylaxis against rheumatic fever and 21 were receiving prophylaxis. A culture of the anterior tooth-gum margin and a culture
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Infectious Disease, Rheumatology, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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