C. Ezrin, M.D.; L. W. Loach, M.D.; S. Neiman, M.D.; M. Barkin, M.D.; T. F. Nicholson, M.B.
This content is PDF only. Please click on the PDF icon to access.
A reversed diurnal excretory rhythm of water, creatinine, and electrolytes was observed in a woman with fluid retention that first appeared after a head injury. Synthetic oxytocin produced a diuresis and restored a normal excretory rhythm. Recumbency for 24 hours also induced a return to normal rhythm. Spontaneous resumption of a normal cycle of renal excretion, even when the patient continued to be up and about during the day, was sometimes observed 1 day before menstruation.
Inulin, PAH, and endogenous creatinine clearance studies showed that oxytocin and recumbency increased the daytime GFR (glomerular filtration rate). In the isolated, perfused dog
Learn more about subscription options.
Register Now for a free account.
Ezrin C, Loach LW, Neiman S, Barkin M, Nicholson TF. Is Oxytocin the Diurnal Regulator of Renal Hemodynamics?. Ann Intern Med. 1963;58:742. doi: 10.7326/0003-4819-58-4-742_1
Download citation file:
Published: Ann Intern Med. 1963;58(4):742.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only