WILLIAM MCFARLAND, M.D., F.A.C.P.; EUGENE P. LIBRE, M.D.
MCFARLAND W., LIBRE E.; Abnormal Leukocyte Response in Alcoholism. Ann Intern Med. 1963;59:865-877. doi: 10.7326/0003-4819-59-6-865
Download citation file:
Published: Ann Intern Med. 1963;59(6):865-877.
Hematologic abnormalities are well-recognized in cirrhosis of the liver and studies to elucidate the cause usually incriminate the advanced liver disease and secondary splenomegaly with resultant hypersplenism. Recently, however, studies have suggested that liver disease and hypersplenism may not be essential etiologic factors. In a group of alcoholic patients studied by Jandl (1), the hematologic findings in two patients led him to suspect a direct suppression of the bone marrow by alcohol. In a later report, McCurdy, Pierce, and Rath (2) have demonstrated vacuolization of erythrocyte precursors in the marrows of acute alcoholics similar to the changes observed in the
to gain full access to the content and tools.
Learn more about subscription options.
Register Now for a free account.
Tobacco, Alcohol, and Other Substance Abuse, Prevention/Screening.
Results provided by:
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only