R. R. SCHUMACHER, M.D.; A. S. RIDOLFO, PH.D., M.D.; B. L. MARTZ, M.D., F.A.C.P.
The properties of the peritoneum as a dialyzing membrane were first explored as early as 1894 to 1895 (1, 2). Subsequent work enlarged upon this early knowledge and demonstrated that:  fluids injected into the peritoneal cavity would change in volume over a short period of time according to the concentration and nature of solutes in the dialyzing fluid (3-7); and  various substances would cross the peritoneum in response to concentration gradients (3, 4, 7-11). It was demonstrated that urea, uric acid, creatinine, and sulfate, as well as chlorbutanol, salicylates, and phenolphthalein (7) would migrate into fluids injected into
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SCHUMACHER RR, RIDOLFO AS, MARTZ BL. Periodic Peritoneal Dialysis for Chronic Renal Failure: A Case Study of Sixteen Months' Experience. Ann Intern Med. 1964;60:296–305. doi: 10.7326/0003-4819-60-2-296
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Published: Ann Intern Med. 1964;60(2_Part_1):296-305.
Chronic Kidney Disease, Nephrology, Renal Replacement Therapy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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