George R. Thompson, M.D.; Milovan T. Rakic, M.D.; William Martel, M.D.; John T. Hayes, M.D.
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It is generally accepted that genetic factors are important in ankylosing spondylitis, hyperuricemia, and gout. While it is probably not a unique association, to our knowledge, there are no reports of these illnesses occurring in the same patient. It therefore seems pertinent to call attention to a family in which hyperuricemia and gout, ankylosing spondylitis, and various developmental anomalies of the lower spine occurred in several members of three generations.
The propositus, a 44-year-old man, had tophaceous gout, ankylosing spondylitis, and a transitional lumbosacral vertebra with spine bifida. Of his eight children, two had ankylosing spondylitis, one of whom also
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Thompson GR, Rakic MT, Martel W, Hayes JT. Ankylosing Spondylitis, Hyperuricemia, and Anomalies of the Lumbosacral Junction: A Family Study.. Ann Intern Med. 1964;60:315. doi: 10.7326/0003-4819-60-2-315_1
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Published: Ann Intern Med. 1964;60(2_Part_1):315.
Infectious Disease, Rheumatology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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