Alton I. Sutnick, M.D. (Associate)
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The production of atelectasis has classically been viewed as a mechanical process involving one of two mechanisms: bronchial obstruction or external compression of the alveoli. Although the existence of nonobstructive atelectasis has been recognized for many years, investigation of the mechanisms involved in this phenomenon has been a relatively recent development.
The forces of surface tension are now generally considered to be a powerful stimulus to alveolar collapse. A naturally occurring antagonist to these forces, pulmonary surfactant, maintains alveolar patency. The activity of this surfactant has been altered under certain experimental conditions and in a number of clinical disease states.
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Sutnick AI. Atelectasis: Recent Concepts.. Ann Intern Med. 1964;60:336. doi: 10.7326/0003-4819-60-2-336_1
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Published: Ann Intern Med. 1964;60(2_Part_1):336.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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