M. LERTZMAN, M.D.; B. M. FROME, M.D.; L. G. ISRAELS, M.D.; R. M. CHERNIACK, M.D., F.A.C.P.
It is generally considered that the demonstration of arterial oxygen unsaturation in a patient with polycythemia indicates a secondary rather than a primary cause for the increase in red cell mass (1-3). While hypoxia has been demonstrated in some patients with polycythemia vera (4-6) it has been attributed in these instances to co-existent cardiorespiratory disease (1, 6) or aging (7).
The present study demonstrates that the arterial oxygen tension may be low in patients with polycythemia vera who have no demonstrable co-existent cardiorespiratory disease and presents evidence that the hypoxia may be the result of an abnormality of the pulmonary
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LERTZMAN M, FROME BM, ISRAELS LG, CHERNIACK RM. Hypoxia in Polycythemia Vera. Ann Intern Med. 1964;60:409–417. doi: 10.7326/0003-4819-60-3-409
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Published: Ann Intern Med. 1964;60(3):409-417.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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