DAVID S. NOUROK, M.D.
NOUROK DS. Familial Pheochromocytoma and Thyroid Carcinoma. Ann Intern Med. 1964;60:1028-1040. doi: 10.7326/0003-4819-60-6-1028
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Published: Ann Intern Med. 1964;60(6):1028-1040.
Pheochromocytoma is a catecholamine-secreting tumor arising either from the adrenal medulla or from chromaffin tissue located elsewhere in the body. A familial occurrence has been demonstrated, with sixteen affected kindred thus far reported (1-15). An association with thyroid carcinoma has also been shown (12, 16, 17) and two recent publications (14, 18) have reported the thyroid carcinoma to be a newly described (19) medullary (solid) carcinoma with amyloid infiltration.
This report will describe the occurrence of bilateral pheochromocytoma and of thyroid carcinoma in a mother and her daughter. The mother died after attempted adrenalectomy 25 years ago. The daughter recently
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Endocrine and Metabolism, Hematology/Oncology, Endocrine Cancer.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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