ALEXANDER M. RUTENBURG, M.D.; BENJAMIN M. BANKS, M.D.; ESTEBAN P. PINEDA, M.D.; JULIUS A. GOLDBARG, M.D.
RUTENBURG AM, BANKS BM, PINEDA EP, GOLDBARG JA. A Comparison of Serum Aminopeptidase and Alkaline Phosphatase in the Detection of Hepatobiliary Disease in Anicteric Patients. Ann Intern Med. 1964;61:50-55. doi: 10.7326/0003-4819-61-1-50
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Published: Ann Intern Med. 1964;61(1):50-55.
Diseases of the liver, bile duct, or pancreas generally produce an increase in serum aminopeptidase activity (LAP) (1-14). This increase signifies excretory blockade (1, 6). The same is true of serum phosphatase, but an increase in this enzyme can also be caused by increased osteoblastic activity (15-26).
Previous reports (1, 3, 4, 6-8, 12, 27-34) have dealt with these serum enzymes in jaundiced patients, but the data on anicteric patients (3-6, 27, 28) are sparse. The purpose of the present report is to assess the relative merits of the serum values of these enzymes in 1,332 anicteric patients, 400 in
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Biliary Disorders, Celiac Disease and Malabsorption, Education and Training, Gastroenterology/Hepatology, Hospital Medicine.
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