L. FREDERICK FENSTER, M.D.; W. WATSON BUCHANAN, M.D.; LEONARD LASTER, M.D.; JOSEPH J. BUNIM, M.D., F.A.C.P.
Sjögren's syndrome is a chronic, benign, systemic disorder of unknown etiology, involving principally the lacrimal and salivary glands and occasionally other mucus-secreting glands such as the buccal, esophageal, and bronchial mucous glands (1). In about one half of the cases it is associated with rheumatoid arthritis and less frequently with systemic lupus erythematosus, progressive systemic sclerosis (scleroderma), and myopathy or polymyositis (1). The histopathology of this disorder consists of infiltration of the secretory parenchyma of the salivary and lacrimal glands by lymphocytes and plasma cells, atrophy of acinar tissue, and proliferation of ductal epithelial cells (2). These changes give
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FENSTER LF, BUCHANAN WW, LASTER L, BUNIM JJ. Studies of Pancreatic Function in Sjögren's Syndrome. Ann Intern Med. 1964;61:498–508. doi: 10.7326/0003-4819-61-3-498
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Published: Ann Intern Med. 1964;61(3):498-508.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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