Maxwell M. Wintrobe, M.D., F.A.C.P.
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The ultimate test of adverse reaction to drugs in man is the observation of the effect of a drug in a human being. While information about the reactions of test animals to certain drugs is essentially circumstantial, it can serve as a warning to the physician. In many instances, such warning will suffice since, in all instances of the use of a drug in a particular case, the possible risk must be weighed against the probable gain. This paper discusses problems related to collecting information concerning adverse reactions, including the cooperative efforts of the AMA and FDA.
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Wintrobe MM. Adverse Reaction Reporting of Drugs.. Ann Intern Med. 1964;61:802. doi: 10.7326/0003-4819-61-4-802_1
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Published: Ann Intern Med. 1964;61(4):802.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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