RALPH C. WILLIAMS, M.D.; EDGAR S. CATHCART, M.D.; EVAN CALKINS, M.D.; GEORGE L. FITE, M.D.; JOSÉ BARBA RUBIO, M.D.; ALAN S. COHEN, M.D.
WILLIAMS RC, CATHCART ES, CALKINS E, FITE GL, RUBIO JB, COHEN AS. Secondary Amyloidosis in Lepromatous Leprosy: Possible Relationships of Diet and Environment. Ann Intern Med. 1965;62:1000-1007. doi: 10.7326/0003-4819-62-5-1000
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Published: Ann Intern Med. 1965;62(5):1000-1007.
Clinical and pathologic studies, conducted at the U. S. Public Health Service Hospital, Carville, La., indicate that amyloidosis is present in approximately one third of the patients with lepromatous leprosy currently at that institution (1, 2). Amyloid deposits have been found at autopsy in 50% of individuals who died during the course of lepromatous leprosy at Carville (3).
The high incidence of amyloidosis in this country, however, is in striking contrast to the apparent incidence in lepromatous patients from other areas of the world such as India, Africa, Mexico, or Japan, where it is regarded as a rare complication of
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Infectious Disease, Mycobacterial Infections.
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