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Four leading authorities in the field present in five chapters a composite and comprehensive coverage of our enlarged understanding of Tay-Sachs' disease.
Leading on from an historical account of the disease, the clinical features are described. It is stressed that affected infants do not in fact appear normal during the first 4 to 6 months of life but that the characteristic motor response to sound can be elicited within a few weeks of birth. Pathogenesis and evolution are traced through gross and histologic anatomy and more clearly delineated with the refinements of histochemistry and electron microscopy. Of special interest is
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Tay-Sachs' Disease.. Ann Intern Med. 1965;62:1104. doi: 10.7326/0003-4819-62-5-1104_1
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Published: Ann Intern Med. 1965;62(5):1104.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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