Peter L. Frommer, M.D.; John Ross Jr., M.D.; Dean T. Mason, M.D.; James H. Gault, M.D.; Eugene Braunwald, M.D., F.A.C.P.
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The development of an accurate, stable, rapidly responding (0.1 sec time constant) fiber-optic catheter system, based on reflectance oximetry, now permits direct continuous recording of intracardiac oxygen saturation and indocyanine green dye concentration without the withdrawal of blood. Oxygen saturation has been recorded continuously for periods of up to 3 hours in 17 patients with congenital or valvular heart disease. The catheter oximeter facilitated precise localization as well as the quantification of left-to-right shunts. Further, it was observed that the flow through ventricular septal defects occurs predominantly during systole, while flow across atrial septal defects varies phasically with both the
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Frommer PL, Ross J, Mason DT, Gault JH, Braunwald E. Clinical Application of an Improved, Rapidly Responding Intravascular Fiber-Optic Catheter.. Ann Intern Med. 1965;63:903. doi: 10.7326/0003-4819-63-5-903_1
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Published: Ann Intern Med. 1965;63(5):903.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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