John H. Lawrence, M.D., F.A.C.P.; John A. Linfoot, M.D.; James L. Born, M.D.; Cornelius A. Tobias, M.D.; Edward Manougian, M.D.
This content is PDF only. Please click on the PDF icon to access.
During the past 10 years we have used an externally delivered alpha-particle or proton beam to treat several hundred patients suffering from various disorders, including 38 patients with acromegaly and 7 patients with Cushing's disease. The high-energy, heavy-particle beam with its advantageous properties of great penetration, little scatter, greater biological effectiveness per unit of ionization in tissue, Bragg peak effect, relative insensitivity to oxygen concentration, and lack of a recovery factor (its effect being predominantly irreversible) makes possible the delivery of large amounts of energy to localized areas within the body without damage to surrounding tissue. Therefore we are able
Learn more about subscription options.
Register Now for a free account.
Lawrence JH, Linfoot JA, Born JL, Tobias CA, Manougian E. Heavy Particle Therapy in Acromegaly and Cushing's Disease.. Ann Intern Med. 1965;63:908. doi: 10.7326/0003-4819-63-5-908_2
Download citation file:
Published: Ann Intern Med. 1965;63(5):908.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only