WILLIAM H. MAHOOD, M.D.; JOHN H. KILLOUGH, M.D., F.A.C.P.
A cute intermittent porphyria has intrigued physicians since its first description in 1889 by Stokvis (1). It was first recognized as a hereditary disorder by Barker and Estes (2) in 1912; however, it was Waldenström (3) in 1937 who firmly established the familial incidence. It has since been shown to be expressed as a dominant character (4). The importance of detecting latent porphyria by studying the members of affected families has been stressed by several investigators (5-7). By protection from unnecessary operations and drugs that aggravate the disease, Waldenström (8) was able to reduce strikingly the mortality in one large
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MAHOOD WH, KILLOUGH JH. Acute Intermittent Porphyria: A Clinical and Laboratory Study of a Large Family. Ann Intern Med. 1966;64:259–267. doi: 10.7326/0003-4819-64-2-259
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Published: Ann Intern Med. 1966;64(2):259-267.
Gastroenterology/Hepatology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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