HELEN I. GLUECK, M.D., F.A.C.P.; WALTER ROEHLL JR., M.D.
This paper reports the occurrence of a myocardial infarction in a patient with an absolute deficiency of the Hageman factor (XII). Myocardial infarction has been described in two patients with hemophilia (VIII) (1, 2) and in a third, widespread atherosclerosis was found at autopsy (3). Likewise, myocardial infarction has recently been reported in a patient with plasma thromboplastin component (PTC) (IX) deficiency (4). To our knowledge, such an episode has not been reported in a patient with the Hageman defect. The simultaneous occurrence of these two disorders is of particular interest, since normally in vitro Hageman factor must be activated
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GLUECK HI, ROEHLL W. Myocardial Infarction in a Patient with a Hageman (Factor XII) Defect. Ann Intern Med. 1966;64:390–396. doi: 10.7326/0003-4819-64-2-390
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Published: Ann Intern Med. 1966;64(2):390-396.
Acute Coronary Syndromes, Cardiology, Coronary Heart Disease, Emergency Medicine.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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