GERALD SALEN, M.D.; FRANZ GOLDSTEIN, M.D., F.A.C.P.; C. WILMER WIRTS, M.D., F.A.C.P.
Small-intestinal involvement in scleroderma has received increasing attention in recent years. Both the radiologic and pathologic features have been described in detail. Segmental dilatation of the jejunum and descending duodenum and delayed intestinal transit are the main radiologic findings (1, 2). Atrophy and fragmentation of the muscular coats with increased deposition of collagen are characteristic histologic features (3, 4); the mucosa is essentially intact (5). Rosson and Yesner (6) recently reported increased deposition of collagen around and between the lobules of Brunner's glands.
Despite the relative frequency of small-intestinal involvement in scleroderma (1, 2, 4) only 11 cases have been
Learn more about subscription options.
Register Now for a free account.
SALEN G, GOLDSTEIN F, WIRTS CW. Malabsorption in Intestinal Scleroderma: Relation to Bacterial Flora and Treatment with Antibiotics. Ann Intern Med. 1966;64:834–841. doi: 10.7326/0003-4819-64-4-834
Download citation file:
Published: Ann Intern Med. 1966;64(4):834-841.
Celiac Disease and Malabsorption, Gastroenterology/Hepatology, Rheumatology, Scleroderma.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only