George R. Green, M.D.; Gustavus A. Peters, M.D., F.A.C.P.; Joseph E. Geraci, M.D., F.A.C.P.
Green GR, Peters GA, Geraci JE. Treatment of Bacterial Endocarditis in Patients with Penicillin Hypersensitivity.. Ann Intern Med. 1966;64:1170. doi: 10.7326/0003-4819-64-5-1170_1
Download citation file:
Published: Ann Intern Med. 1966;64(5):1170.
This content is PDF only. Please click on the PDF icon to access.
Seventy-one of 400 patients treated for bacterial endocarditis (1951 through 1964) had a history of penicillin allergy (18%). Allergic reactions occurred in 22 of 56 such patients receiving penicillin (39%); 18 patients without allergic history had reactions to penicillin (5%). No reaction was fatal, but one patient had an anaphylactic reaction. In 5 of 22 patients in the allergic group and in 5 of 18 in the nonallergic group, penicillin therapy was discontinued because of severe reactions but was successfully completed in the others, the delayed allergic reaction being controlled by steroids or antihistamines or both. Little correlation was noted
Learn more about subscription options.
Register Now for a free account.
Cardiology, Endocarditis, Infectious Disease.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only