ROBERT A. GREEN, M.D.; VINCENT L. FROMKE, M.D.
Splenomegaly occurs in uncomplicated rheumatoid arthritis in about 5 to 10% of patients, but the association of splenomegaly, arthritis, and leukopenia, known as Felty's syndrome, is quite rare, perhaps in the range of 1 in 300 cases of rheumatoid arthritis. Anemia and occasionally thrombocytopenia may also occur, and these cytopenias have most often been explained as being due to hypersplenism. Hypersplenism is an uncertain concept at best, and in a pathologic condition such as rheumatoid arthritis, the relationship of the enlarged spleen and abnormalities in the blood should be considered cautiously. This is particularly true when it comes to the
Learn more about subscription options.
Register Now for a free account.
GREEN RA, FROMKE VL. Splenectomy in Felty's Syndrome. Ann Intern Med. 1966;64:1265-1270. doi: 10.7326/0003-4819-64-6-1265
Download citation file:
Published: Ann Intern Med. 1966;64(6):1265-1270.
Rheumatoid Arthritis, Rheumatology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only