JAMES C. GUCKIAN, M.D.; JOHN E. PERRY, M.D.
Granulomas in the liver may result from many diseases of man. One of the most perplexing problems in medicine is to arrive at a diagnosis in a patient whose liver biopsy shows noncaseating granulomas in the absence of identifiable organisms. This is not an uncommon problem as reflected by a 3 to 10% prevalence of granulomas in liver biopsies performed at general hospitals (1-4). There are several reviews of hepatic granulomas (4-7), and Table 1 lists the various diseases with which they have been associated.
Although there are many causes for granulomatous hepatitis, it is probable that the pathogenesis is
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GUCKIAN JC, PERRY JE. Granulomatous Hepatitis: An Analysis of 63 Cases and Review of the Literature. Ann Intern Med. 1966;65:1081–1100. doi: 10.7326/0003-4819-65-5-1081
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Published: Ann Intern Med. 1966;65(5):1081-1100.
Gastroenterology/Hepatology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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