WILLIAM C. HOLLIS, M.D.
Hypertrophic osteoarthropathy is a relatively common syndrome of marked diagnostic significance (1-4) yet infrequently recognized. It is important in that it is often an early manifestation of an occult disease, frequently a malignancy, still in a curable stage. Erroneous diagnoses are common and include acromegaly, myxedema, Paget's disease, and rheumatoid arthritis; yet the distinction is usually clear once the diagnosis is considered. The disease was first described in 1890 by Marie, in a case which was quite typically originally erroneously diagnosed as acromegaly. Bamberger in 1891 also described the syndrome. The eponym, Marie-Bamberger syndrome, is often used.
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HOLLIS WC. Hypertrophic Osteoarthropathy Secondary to Upper-gastrointestinal-tract Neoplasm: Case Report and Review. Ann Intern Med. 1967;66:125–130. doi: 10.7326/0003-4819-66-1-125
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Published: Ann Intern Med. 1967;66(1):125-130.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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